Magnesium

	In which conditions is magnesium beneficial?
	What are the various types of drugs that cause magnesium depletion?
	What are the physical signs of magnesium deficiency?
	What are the various tests that can be used to monitor magnesium levels and what are the pros and cons?
	Should magnesium be used for hypertension alone or only with a diuretic to prevent magnesium deficiency?
	Is there a benefit to having magnesium released slowly over a period of time, rather than a peak and decline within hours?
	How much magnesium should patients receive per day?

Blaine Mag-Ox 400

	What is the difference between Mag-Ox 400 and other products?
	How long should my patients take Mag-Ox 400?
	What are the dosing recommendations for Mag-Ox 400?
	What are the side effects of Mag-Ox 400?
	Can one overdose on magnesium supplements?
	How can I get samples and/or more information for Mag-Ox 400?
	Where is Mag-Ox 400 available?
	Why is Mag-Ox 400 located behind the counter — do I need to write a prescription?
	What does Blaine Pharmaceuticals offer to healthcare professionals?
	Why should I proactively recommend magnesium supplementation for my type 2 diabetic patients?
	Do you support research and grants for clinical trials? How can I apply for one of these?

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⁷ National Institutes of Health
⁸ Kendall, David, M., M.D. (2004). Targeting Insulin Resistance: Diabetes Prevention, Cardiovascular Disease Risk, and the Thiozolidinediones. In Medscape Coverage of American Diabetes Association 64th Annual Scientific Sessions. http://www.medscape.com/viewarticle/482449
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¹³ Rodriguez-Moran, M & Guerrero-Romero, F. (2003). Oral magnesium supplementation improves insulin sensitivity and metabolic control in type 2 diabetic subjects. Diabetes Care: 26(3), 1147-1152.
¹⁴ Guerrero-Romero, F., et. al. (2004). Oral magnesium supplementation improves insulin sensitivity in non-diabetic subjects with insulin resistance. Diabetes Metabolism: 30(3), 253-8. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15223977
¹⁵ Guerrero-Romero, F. & Rodriguez-Moran, M. (2002). Low serum serum magnesium levels and metabolic syndrome. Acta Diabetologica: 39(4)- 209-13. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12486495
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¹⁷ Eibl, Nicole L., et. al. (1995). Hypomagnesemia in type II diabetes: effect of a 3-month replacement therapy. Diabetes Care: 18(2), 188-92.
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¹⁹ Jee, Sun Ha, et. al. (2002). The effect of magnesium supplementation on blood pressure: a meta-analysis of randomized clinical trials. American Journal of Hypertension: 15(8), 691-696.
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²¹ Moser, Marvin, Basile, Jan & Sica, Domenic (2003). Roundtable discussion: electrolytes in cardiovascular disease and hypertension. The Journal of Clinical Hypertension: 5(6), 402-407.
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²³ Zehender, Manfred, et. al. (1997). Antiarrhythmic effects of increasing the daily intake of magnesium and potassium in patients with frequent ventricular arrhythmias. Journal of the American College of Cardiology: 29(5), 1028-1034.
²⁴ Farvid, Maryam Sadat, et. al. (2004). The impact of vitamin and/or mineral supplementation on lipid profiles in type 2 diabetes. Diabetes Research and Clinical Practice: 65, 21-28.
²⁵ Shechter, Michael, et. al. (2002). Low intracellular magnesium levels promote platelet-dependent thrombosis in patients with coronary artery disease. American Heart Journal: 140(2), 211-218.
²⁶ Shechter, Michael, et. al. (1999). Oral magnesium supplementation inhibits platelet-dependent thrombosis in patients with coronary artery disease. The American Journal of Cardiology: 84, 152-156.